A novel muramyl peptide derivative stimulates tumoricidal activity of macrophages and antibody production by B cells.
نویسندگان
چکیده
A novel analog of MDP, the 3'-iodo-4'-azido-L-phenylalanine methyl ester derivative of N-acetyl-L-alanyl-D-isoglutamine, has been prepared. This compound is capable of activating macrophages to the tumoricidal state and increasing the specific immune response of B cells. It thus appears to exhibit similar biological activities to MDP. Moreover, this compound is of potential interest for receptor photolabelling studies.
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ورودعنوان ژورنال:
- FEBS letters
دوره 220 1 شماره
صفحات -
تاریخ انتشار 1987